Daníel F. Guðbjartsson (03/10/14)

Benedikt Magnússon, October 1, 2014

Statistics Colloquium

Speaker: Daníel F. Guðbjartsson, Department of Statistics, deCODE genetics
Title: Estimating the effect of a sequence variant on correlated phenotypes

Location: Lögberg, 201
Time: Friday October 3 at 12:00-13:00.

Abstract:

Some variations in the human genome associate with multiple correlated phenotypes. This leads naturally to questions about conditional independence. E.g.: Given the association between a sequence variant and a phenotype, is the association between the variant and a second phenotype significant? It is relatively easy to create statistical tests for conditional independence but concluding about biological mechanisms from
the results of these tests must be done with great care. This is demonstrated through several important examples.