Daníel F. Guðbjartsson (03/10/14)

Benedikt Magnússon, október 1, 2014

Málstofa í tölfræði

Fyrirlesari: Daníel F. Guðbjartsson, Department of Statistics, deCODE genetics
Titill: Estimating the effect of a sequence variant on correlated phenotypes

Staðsetning: Lögberg, 201
Tími: Föstudagur 3. október , frá 12:00 til 13:00.

Ágrip:

Some variations in the human genome associate with multiple correlated phenotypes. This leads naturally to questions about conditional independence. E.g.: Given the association between a sequence variant and a phenotype, is the association between the variant and a second phenotype significant? It is relatively easy to create statistical tests for conditional independence but concluding about biological mechanisms from
the results of these tests must be done with great care. This is demonstrated through several important examples.